Totally! Arcadia is based on the Clojure-CLR port (an official project) maintained by David Miller for five years or so. It supports Mono.
We had to fork the compiler to introduce a small number of changes to make Arcadia work in Unity, though. Unity ships a very old version of Mono with their own changes, so stock Clojure-CLR would not work.
That would be amazing! Can you invoke command line scripts from LT? If so you could just use our included REPL client implemented in Ruby. Otherwise you'd have to port it to ClojureScript, but the client is designed to be simple enough to make that easy to do.
Yep, though it's not as easy as it could be yet. The best way currently is to write your own command leveraging our spawning APIs (a thin wrapper around node's child_process module with some extra cljs sugar).
We had to fork the compiler to introduce a small number of changes to make Arcadia work in Unity, though. Unity ships a very old version of Mono with their own changes, so stock Clojure-CLR would not work.
https://github.com/clojure/clojure-clr https://github.com/arcadia-unity/clojure-clr