I've really enjoyed playing with Quantopian, and I think that I will continue to play with it as an educational tool. However my algorithms so far have been very good at losing an awful lot of money, so I think I will be sticking with simulations for now :)
A few years ago I heard a story from an acquaintance working at an online spread betting company. One senior figure suggested that they should actively bet against their worst performing customers rather than hedging, they discovered pretty quickly that this wasn't a good idea!