Some of the most admired people are severely depressed and suicidal, people you would consider to be "contributing" and outstanding members of society. I must say, I don't think you have any clue what you are talking about and your "evolutionary" theory is just abominable and the relocation theory is childish. These feelings follow you wherever you go, relocating might temporarily give momentum but without proper help it is useless if we are talking suicide and severe depression.