Personally, I'd say yes. I started out with Merlin 3D and Autocad way back in the day, and of course, Blender is a whole other beast. Took me some time to get used to it, but once I did, I found 3D made a lot more sense than it ever had in those other applications.

Of course, YMMV, but I'd say you should give it a shot. Even just poking around is a start.