On the rare occasions I need one of them, it's rarely one of the common ones. I work with a lot of music scores with lots of weird French and Germany characters that are a little more involved.
On the Mac, it's quite easy to have customized keyboard layouts to make it easy to type characters you use frequently. If you want to have Option-f and Option-p to give you 𝆑 and 𝆏, you can. https://software.sil.org/ukelele/ is a nice GUI that lets you start from your current preferred layout and make changes.