How do you deal with the validation problems that crop up, the data entry problems that crop up, and the impedance mismatch between a traditional datastore and the sheet?
Google sheets actually has a pretty robust data validation setup (up to regular expressesions), and most business users are fairly good at handling detailed instructions.
But yes, for the inevitable times when they get it wrong, you just need some robust alerting system. Having it email/text me when anything goes wrong turned out to still be easier than writing our own CRUD app or fancy interfaces.