Yup, the connection to self-replication has showed up mostly in the discussion here, in relation to true self-replicating patterns like the https://conwaylife.com/wiki/0E0P_metacell -- which does have a few vaguely cell-like attributes.
The RCT design is very much a mathematical construct, as opposed to anything with a biological inspiration. And the RCT's ability to construct itself is more of a theoretical afterthought at this point -- the engineering work hasn't been done yet to produce a demo of that kind of thing.
The point is well taken, about the fragility of Conway's Life with respect to environmental noise. That topic has also come up here and there in these comments, e.g., https://news.ycombinator.com/item?id=33797799#33800301
The RCT design is very much a mathematical construct, as opposed to anything with a biological inspiration. And the RCT's ability to construct itself is more of a theoretical afterthought at this point -- the engineering work hasn't been done yet to produce a demo of that kind of thing.
The point is well taken, about the fragility of Conway's Life with respect to environmental noise. That topic has also come up here and there in these comments, e.g., https://news.ycombinator.com/item?id=33797799#33800301