I don't want to start providing e-mail service for my clients, but recent incidents with my current provider have driven me to take my business elsewhere, or roll my own.
What do you use for an e-mail provider, if you run your own servers for your app?
If you do/don't run your own mail server, why?
I used to manage an email server and it was not very pleasant for someone who just wanted to hack. :-) If you do end up running your own mail server(s) you'll want to be sure you have good spam/virus filtering or users will start complaining. I had really good luck installing Postini a couple years ago -- reduced spam by nearly 100%.