Yes. Search YouTube for high-altitude simulation chambers and hypoxia. I seem to think Derek from Veritasium has a very good demonstration where he gets euhporic and seems unaware that he's severely mentally compromised.
Also, I once helped a friend set up and tear down an art project that was a flying remote-controlled statue, held up partially by a weather balloon full of helium. In tearing down, I didn't want to let the helium go to waste. My first breath of pure helium went fine. My second full breath of pure helium in a row, I barely had enough time to sit down, say "whoah" and cough the helium out before falling down and twitching on the gymnasium floor. A woke up right at the same time my artist friend realized I wasn't joking around. Had I died, I would have felt no pain, not even the slightest discomfort.
Breathing pure helium, I learned you have about 1-2 seconds of warning that you're hypoxic before you pass out. I figured it was more like 15-30 seconds. Luckily, I didn't die, partially because, as a low molecular weight gas, helium has a high rate of effusion, and on my back, it being lighter than air helped it escape my lungs. Argon may very well have killed me because it has a much lower rate of effusion, and (also related to its higher molar mass) it's also heavier than air.
Also, I once helped a friend set up and tear down an art project that was a flying remote-controlled statue, held up partially by a weather balloon full of helium. In tearing down, I didn't want to let the helium go to waste. My first breath of pure helium went fine. My second full breath of pure helium in a row, I barely had enough time to sit down, say "whoah" and cough the helium out before falling down and twitching on the gymnasium floor. A woke up right at the same time my artist friend realized I wasn't joking around. Had I died, I would have felt no pain, not even the slightest discomfort.
Breathing pure helium, I learned you have about 1-2 seconds of warning that you're hypoxic before you pass out. I figured it was more like 15-30 seconds. Luckily, I didn't die, partially because, as a low molecular weight gas, helium has a high rate of effusion, and on my back, it being lighter than air helped it escape my lungs. Argon may very well have killed me because it has a much lower rate of effusion, and (also related to its higher molar mass) it's also heavier than air.