I think what Trey & Matt give us in South Park comes from a pretty genuine, sincere place, most of the time. Sometimes its some of the best comedic satire ever conceived and just the kind of thing we need in the moment - other times, there's nothing particularly inspired and its pretty apparent they just need to get an episode shipped.

But... they have a rare talent for nuking sacred cows from orbit. It always hurts when its your cow.