Why the "not too much"? IIRC Adblock was "compromised" in a way because it was more profitable for them to make deals with advertisers. If they made more money off of donations they wouldn't need to sell out.
Well, it was kind of humourous, based on the idea that ad-tech will switch to first-party proxies when too many people use Pi-Hole.
But on a more serious note, it is simple products like AdGuard DNS which will probably make Ad-Tech sweat more, because it's so easy to use for average users.
Adblock was compromised due to lack of integrity imho.
Pi-Hole is a bit different too in that they do not maintain any block lists. It does come pre-installed with several lists, but maintained by 3rd parties. Its also very easy to add items to the block lists or import new lists. I think having this separation of powers is wonderful and will aid in the protection of the project.